The run-flat options on BMWs have been very uncommon. I have never seen an E46 that had this option, and I think in the past years I have seen 3 740iL's with the option. I guess that shows its popularity, at least here in the Northeast.
Since you don't really have a choice, I would go with it. The sport seats alone are worth it, and in the end, if you don't like the tires you can change them MUCH cheaper than it would cost to retrofit sport seats! That being said, you don't have much of a choice anyways, since BMW does not offer a sport wheel/tire combo on the 330xi/325xi even if equipped with the sport package. The run-flats can't really be worse than the all-seasons, can they??
The Tire Pressure Monitor is just another idiot light in the instrument display.